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BPC-157

BPC-157

$47.00
$47.00
SAVE Liquid error (snippets/price line 116): Computation results in '-Infinity'% Sold out

science Lab-Tested 99% Purity

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BPC-157

BPC-157

$47.00
$47.00
SAVE Liquid error (snippets/price line 116): Computation results in '-Infinity'% Sold out

BPC-157 (Body Protection Compound-157) is a synthetic peptide fragment derived from a protein found in gastric juice. It has been studied for its potential to accelerate wound healing, promote angiogenesis, protect the gastrointestinal tract, and support musculoskeletal repair through modulation of growth and repair pathways.

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  • DESCRIPTION
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  • REFERENCES

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide (15 amino acids) derived from a protective protein found in gastric juice. It has been extensively studied in animal models for its regenerative, angiogenic, and cytoprotective properties. Unlike many peptides, BPC-157 is reported to be stable in gastric juice and effective through multiple administration routes, making it a candidate of significant interest in tissue repair and inflammation research.

Structure

  • Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
  • Molecular Weight: ~1,419 Da
  • Type: Synthetic pentadecapeptide derived from a gastric protein

Research

Gastrointestinal & Organ Protection

BPC-157 has shown robust protective effects in the gastrointestinal tract. Animal studies demonstrate:

  • Protection against ulcer formation (gastric and intestinal)
  • Healing of fistulas and anastomoses
  • Improved recovery after liver and pancreas injury

Vascular & Angiogenic Effects

BPC-157 enhances angiogenesis (blood vessel formation), crucial for tissue healing. Studies show accelerated healing of tendon-to-bone injuries, muscle tears, and skin wounds. It also counteracts vascular lesions induced by NSAIDs, alcohol, and other toxins.

Musculoskeletal & Nerve Repair

In preclinical models, BPC-157:

  • Promotes tendon and ligament healing
  • Improves bone repair and joint recovery
  • Accelerates regeneration of peripheral nerves
  • Enhances functional recovery after traumatic brain injury or spinal cord injury

Anti-inflammatory & Cytoprotective Actions

Research suggests BPC-157 reduces pro-inflammatory cytokines, protects endothelial integrity, and modulates the nitric oxide (NO) system. This underlies its potential in treating systemic inflammation, oxidative stress, and organ damage.

Safety Profile

Animal studies consistently report no toxicity or adverse reactions, even at high doses. However, controlled human clinical studies remain limited, so its safety and efficacy in clinical use remain under investigation.

Summary

BPC-157 is a gastric-derived synthetic pentadecapeptide with wide-ranging tissue-protective and regenerative properties in preclinical studies. Research highlights include:

  • Healing of muscle, tendon, ligament, and bone injuries
  • Protection of the GI tract, liver, and pancreas
  • Angiogenic and anti-inflammatory activity
  • Potential roles in neurological and vascular repair

Its stability and broad cytoprotective profile make BPC-157 a highly promising compound in regenerative medicine research.

This peptide is supplied as a lyophilized powder. Store vials in a cool, dry environment at 2–8 °C, protected from light and moisture. For long-term preservation, store unopened vials at −20 °C. After reconstitution, use under sterile conditions, refrigerate at 2–8 °C, and use promptly. Avoid repeated freeze–thaw cycles to preserve peptide stability.

1. Sikiric P, et al. Stable gastric pentadecapeptide BPC-157 heals various gastrointestinal lesions. World J Gastroenterol. 2010;16(24):3103–3110. doi:10.3748/wjg.v16.i24.3103

2. Seiwerth S, et al. Stable gastric pentadecapeptide BPC-157: novel therapy in wound healing. Curr Pharm Des. 2018;24(18):2012–2035. doi:10.2174/1381612824666180703111630

3. Vukojevic J, et al. BPC-157 and vascular protection: interaction with nitric oxide system. PLoS One. 2014;9(12):e116062. doi:10.1371/journal.pone.0116062

4. Staresinic M, et al. BPC-157 accelerates healing of transected rat Achilles tendon. J Orthop Res. 2003;21(5):976–983. doi:10.1016/S0736-0266(03)00046-6

5. Pevec D, et al. Effects of BPC-157 on bone healing in rats. Bone. 2010;47(1):151–159. doi:10.1016/j.bone.2010.04.588

6. Brcic L, et al. BPC-157 and liver protection in animal models. Liver Int. 2005;25(3):595–602. doi:10.1111/j.1478-3231.2005.01065.x

7. Gjurasin M, et al. Pain modulation by BPC-157 in rodent models of nerve injury. Reg Anesth Pain Med. 2012;37(3):309–314. doi:10.1097/AAP.0b013e31824f9c16

8. Seiwerth S, et al. BPC-157 and brain injury recovery. CNS Neurol Disord Drug Targets. 2015;14(4):544–553. doi:10.2174/1871527314666150330205552

9. Sikiric P, et al. BPC-157 counteracts NSAID-induced GI and vascular lesions. Curr Pharm Des. 2014;20(7):1121–1125. doi:10.2174/1381612820666140128150050

10. Staresinic M, et al. BPC-157 and anastomosis healing: implications for surgery. Surg Today. 2013;43(10):1105–1116. doi:10.1007/s00595-012-0378-4